{"id":103875,"date":"2023-12-19T23:07:49","date_gmt":"2023-12-19T23:07:49","guid":{"rendered":"https:\/\/science-hub.click\/%E3%82%A2%E3%83%90%E3%82%AB%E3%83%93%E3%83%AB%E3%81%AB%E3%81%A4%E3%81%84%E3%81%A6%E8%A9%B3%E3%81%97%E3%81%8F%E8%A7%A3%E8%AA%AC\/"},"modified":"2023-12-19T23:07:49","modified_gmt":"2023-12-19T23:07:49","slug":"%E3%82%A2%E3%83%90%E3%82%AB%E3%83%93%E3%83%AB%E3%81%AB%E3%81%A4%E3%81%84%E3%81%A6%E8%A9%B3%E3%81%97%E3%81%8F%E8%A7%A3%E8%AA%AC","status":"publish","type":"post","link":"https:\/\/science-hub.click\/?p=103875","title":{"rendered":"\u30a2\u30d0\u30ab\u30d3\u30eb\u306b\u3064\u3044\u3066\u8a73\u3057\u304f\u89e3\u8aac"},"content":{"rendered":"

\u5c0e\u5165<\/h2>
\n\"\"<\/figure>
2 \u30a2\u30d0\u30ab\u30d3\u30eb 300mg <\/div><\/div><\/div>
\u30a2\u30d0\u30ab\u30d3\u30eb<\/th><\/tr>
\n\"\u30a2\u30d0\u30ab\u30d3\u30eb\u306e\u5e73\u9762\u8868\u73fe\"<\/figure><\/td><\/tr>
\u4e00\u822c\u7684\u306a<\/th><\/tr>
IUPAC\u540d<\/td><\/tr>
\u540c\u7fa9\u8a9e<\/td>ABC<\/td><\/tr>
CAS\u756a\u53f7<\/sup><\/td>136470-78-5<\/span><\/span><\/td><\/tr>
ATC\u30b3\u30fc\u30c9<\/td>J05<\/span><\/span> AF06<\/span><\/span><\/td><\/tr>
\u30c9\u30e9\u30c3\u30b0\u30d0\u30f3\u30af<\/td>DB01048<\/span><\/td><\/tr>
\u30d1\u30d6\u30b1\u30e0<\/td>441300<\/span><\/td><\/tr>
\u7b11\u9854<\/td><\/tr>
\u30a4\u30f3\u30c1\u30c1<\/td><\/tr>
\u5316\u5b66\u7684\u6027\u8cea<\/th><\/tr>
\u751f\u306e\u30d5\u30a9\u30fc\u30df\u30e5\u30e9<\/td>C 14<\/sub> H 18<\/sub> N 6<\/sub> W<\/td><\/tr>
\u30e2\u30eb\u8cea\u91cf<\/a><\/span><\/td>286.3323 \u00b1 0.014 g mol -1<\/sup><\/td><\/tr>
\u7269\u7406\u7684\u6027\u8cea<\/th><\/tr>
\u878d\u89e3<\/a><\/span>\u6e29\u5ea6<\/td>165<\/span> \u2103<\/abbr><\/td><\/tr>
\u30bb\u30e9\u30d4\u30fc<\/a><\/span>\u30af\u30e9\u30b9<\/th><\/tr>
\u6297\u30a6\u30a4\u30eb\u30b9\u5264\u30fb\u6297\u30ec\u30c8\u30ed\u30a6\u30a4\u30eb\u30b9\u5264\u30fb\u30cc\u30af\u30ec\u30aa\u30b7\u30c9\u9006<\/a><\/span>\u8ee2\u5199\u9175\u7d20\u963b\u5bb3\u5264<\/span><\/td><\/tr>
\u85ac\u7269\u52d5\u614b\u30c7\u30fc\u30bf<\/a><\/span><\/th><\/tr>
\u30d0\u30a4\u30aa\u30a2\u30d9\u30a4\u30e9\u30d3\u30ea\u30c6\u30a3<\/td>83%<\/span><\/td><\/tr>
\u30bf\u30f3\u30d1\u30af\u8cea\u306e\u7d50\u5408<\/td>50%<\/span>\u8fd1\u304f<\/td><\/tr>
\u4ee3\u8b1d<\/a><\/span><\/td>\u809d\u81d3<\/td><\/tr>
\u9664\u53bb\u534a\u6e1b\u671f<\/a><\/span><\/td>1.54\u00b10.63\u6642\u9593<\/a><\/span><\/td><\/tr>
\u6cbb\u7642\u4e0a\u306e\u8003\u616e\u4e8b\u9805<\/th><\/tr>
\u6295\u4e0e\u7d4c\u8def<\/td>\u30aa\u30fc\u30e9\u30eb<\/td><\/tr>
\u598a\u5a20<\/a><\/span><\/td>\u7981\u5fcc<\/td><\/tr>
\u7279\u306b\u6307\u5b9a\u306e<\/a><\/span>\u306a\u3044\u9650\u308a\u3001SI \u304a\u3088\u3073 CNTP \u5358\u4f4d\u3002<\/center><\/td><\/tr><\/table>
\u30a2\u30d0\u30ab\u30d3\u30eb<\/b><\/td><\/tr><\/table><\/th><\/tr>
\u5546\u54c1\u540d\uff1a<\/b> Ziagen\u00ae (\u30d9\u30eb\u30ae\u30fc\u3001\u30d5\u30e9\u30f3\u30b9\u3001\u30b9\u30a4\u30b9)<\/td><\/tr>
\u30af\u30e9\u30b9 \uff1a<\/b>\u6297\u30a6\u30a3\u30eb\u30b9\u85ac<\/td><\/tr>
\u305d\u306e\u4ed6\u306e\u60c5\u5831:<\/b>\u30b5\u30d6\u30af\u30e9\u30b9:<\/b><\/td><\/tr><\/table>

\u30a2\u30d0\u30ab\u30d3\u30eb<\/b>(ABC) \u306f\u3001HIV \u611f\u67d3\u75c7\u306e\u6cbb\u7642\u306b\u4f7f\u7528\u3055\u308c\u308b\u975e\u5e38\u306b\u5f37\u529b\u306a\u9006\u8ee2\u5199\u9175\u7d20\u963b\u5bb3\u5264\u3067\u3059\u3002 ABC\u306f\u8840\u6db2\u8133\u95a2\u9580\u3092\u901a\u904e\u3059\u308b\u3053\u3068\u304c\u3067\u304d\u307e\u3059\u3002\u305d\u308c\u306f\u3080\u3057\u308d\u3088\u304f\u8a31\u5bb9\u3055\u308c\u307e\u3059\u3002\u4e3b\u306a\u526f\u4f5c\u7528\u306f\u904e\u654f\u53cd\u5fdc\u3067\u3042\u308a\u3001\u5371\u967a\u306a\u5834\u5408\u304c\u3042\u308a\u307e\u3059\u3002<\/p>

AZT \u307e\u305f\u306f 3TC \u306b\u8010\u6027\u306e\u3042\u308b\u682a\u306f\u4e00\u822c\u306b\u30a2\u30d0\u30ab\u30d3\u30eb\u306b\u611f\u53d7\u6027\u304c\u3042\u308a\u307e\u3059\u304c\u3001AZT\u304a\u3088\u3073<\/i>3TC \u306b\u8010\u6027\u306e\u3042\u308b\u682a\u306f\u30a2\u30d0\u30ab\u30d3\u30eb\u306b\u5bfe\u3057\u3066\u3042\u307e\u308a\u611f\u53d7\u6027\u304c\u3042\u308a\u307e\u305b\u3093\u3002\u30a2\u30d0\u30ab\u30d3\u30eb\u306f\u7d4c\u53e3\u6295\u4e0e\u3055\u308c\u3001\u9ad8\u3044\u751f\u7269\u5b66\u7684\u5229\u7528\u80fd (83%) \u3092\u6301\u3063\u3066\u3044\u307e\u3059\u3002\u3053\u308c\u306f\u4e3b\u306b\u30015’\u672b\u7aef\u306e\u4e00\u7d1a\u30a2\u30eb\u30b3\u30fc\u30eb\u3092\u30ab\u30eb\u30dc\u30f3\u9178<\/a><\/span>\u307e\u305f\u306f\u30b0\u30eb\u30b3\u30cb\u30eb\u30c8\u30e9\u30f3\u30b9\u30d5\u30a7\u30e9\u30fc\u30bc<\/a><\/span><\/span>\u306b\u5909\u63db\u3059\u308b\u30a2\u30eb\u30b3\u30fc\u30eb\u30c7\u30d2\u30c9\u30ed\u30b2\u30ca\u30fc\u30bc<\/span>\u306b\u3088\u3063\u3066\u4ee3\u8b1d\u3055\u308c\u307e\u3059\u3002<\/p>

\u3053\u306e\u85ac\u306f<\/a><\/span>\u3001 Ziagen<\/span> (GlaxoSmithKline) \u306e\u30d6\u30e9\u30f3\u30c9\u540d\u3067\u3001\u307e\u305f Trizivir (GlaxoSmithKline) \u3068 Kivexa (GlaxoSmithKline) \u306e\u7d44\u307f\u5408\u308f\u305b\u3068\u3057\u3066\u8ca9\u58f2\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>

\n\"\u30a2\u30d0\u30ab\u30d3\u30eb\u306b\u3064\u3044\u3066\u8a73\u3057\u304f\u89e3\u8aac\"<\/figure>

\u526f\u4f5c\u7528<\/h2>

\u75c7\u4f8b\u306e 5 \uff5e 10% \u3067\u306f\u3001\u85ac\u7269\u6295\u4e0e\u5f8c\u6570\u9031\u9593\u3067\u767a\u71b1<\/a><\/span>\u3001\u767a\u75b9\u3001\u606f\u5207\u308c\u3001\u6d88\u5316\u5668\u75c7\u72b6\u306a\u3069\u306e\u904e\u654f\u75c7\u75c7\u5019\u7fa4<\/a><\/span>\u304c\u767a\u751f\u3057\u307e\u3059\u304c\u3001\u3053\u308c\u3089\u306f\u3059\u3079\u3066<\/a><\/span>\u6cbb\u7642\u306e\u4e2d\u6b62\u304c\u5fc5\u8981\u3067\u3059\u304c\u3001\u305d\u306e\u5f8c\u306f\u5b8c\u5168\u306b\u56de\u5fa9\u3057\u307e\u3059\u3002\u3053\u306e\u53cd\u5fdc\u306f\u3001HLA-B*5701 \u5bfe\u7acb\u907a\u4f1d\u5b50\u306e\u5b58\u5728\u3068\u5bc6\u63a5\u306b\u95a2\u9023\u3057\u3066\u3044\u308b\u3088\u3046\u3067\u3059\u3002<\/p>

\u6cbb\u7642\u3092\u53d7\u3051\u3066\u3044\u308b\u60a3\u8005\u304c\u5fc3\u7b4b\u6897\u585e\u3092<\/a><\/span>\u8d77\u3053\u3059<\/a><\/span>\u30ea\u30b9\u30af\u3082\u9ad8\u304f\u306a\u308a\u307e\u3059\u3002<\/p><\/div>

\u53c2\u8003\u8cc7\u6599<\/h2>
  1. Abakavir \u2013 afrikaans<\/a><\/li>
  2. \u0623\u0628\u0627\u0643\u0627\u0641\u064a\u0631 \u2013 arabe<\/a><\/li>
  3. \u0627\u0628\u0627\u06a9\u0627\u0648\u06cc\u0631 \u2013 South Azerbaijani<\/a><\/li>
  4. \u0985\u09cd\u09af\u09be\u09ac\u09be\u0995\u09be\u09ad\u09bf\u09b0 \u2013 bengali<\/a><\/li>
  5. Abakavir \u2013 tch\u00e8que<\/a><\/li>
  6. Abacafir \u2013 gallois<\/a><\/li><\/ol><\/div>\n
    \n

    \n \u30a2\u30d0\u30ab\u30d3\u30eb\u306b\u3064\u3044\u3066\u8a73\u3057\u304f\u89e3\u8aac\u30fb\u95a2\u9023\u52d5\u753b\n <\/h2>\n
    \n \n
    \n
    \n